Sudan Virus Disease (SVD)
6.Sudan Virus Disease (SVD): The Ugandan government and the World Health Organization recently confirmed an outbreak of Sudan virus disease.
- About: Sudan virus disease is a viral hemorrhagic fever disease, belonging to the same family as Ebola virus disease, caused by Sudan virus (SUDV). It is a severe disease with high case fatality.
- Symptoms & Progression:
o Early symptoms: Fever, abdominal pain, anorexia, fatigue, malaise, myalgia, sore throat.
o Later symptoms: Nausea, vomiting, diarrhea, variable rash, hiccups.
o Severe illness: Hemorrhagic manifestations (bleeding, ecchymoses, petechiae, visceral effusions), encephalopathy, shock, multi-organ failure, spontaneous abortion in pregnant women.
o Recovery issues: Arthralgia, neurocognitive dysfunction, uveitis (may lead to cataracts).
o Persistent infection possible in immune-privileged compartments (CNS, eyes, testes).
o Ebola vaccines are ineffective against Sudan virus.
- Transmission & Risk Factors:
o Person-to-person transmission via direct contact with blood, bodily fluids, organs, or contaminated surfaces.
o Higher risk groups: Family members, healthcare providers, burial participants.
o Risk increases with disease severity.
Detailed Solutions & Explanations
