Shingles Vaccine : Recent studies highlight added benefits of the shingles vaccine beyond infection prevention.
o Research from South Korea links it to a 23% lower risk of cardiovascular disease, while a Welsh study suggests it may also reduce the risk of dementia.
o Symptoms: Appears as a painful, itchy rash on one side of the body, often in a band or stripe. Can lead to complications like postherpetic neuralgia (persistent nerve pain).
o Risk: After a chickenpox infection, the virus remains dormant and may reactivate later in life as shingles.
o Vaccines: Zostavax – a live-attenuated vaccine, used in the Welsh study exploring links between shingles vaccination and reduced dementia risk.
ü Shingrix – a recombinant vaccine, more widely used. A 2024 Oxford study found that vaccinated individuals in the U.S. had a 17% lower risk of dementia over six years.
o Symptoms: Memory loss, behavior changes, and reduced ability to perform everyday tasks.
o Common Types:
ü Alzheimer’s Disease: Most common, with progressive memory and cognitive decline.
ü Vascular Dementia: Caused by blood flow issues in the brain.
ü Mixed Dementia: Combination of multiple dementia types.
o Other Causes: Conditions like thyroid disorders or vitamin deficiencies can mimic dementia symptoms but are treatable.
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The UPSC Civil Services Exam has three parts:
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