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Context: The Indian Council of Medical Research (ICMR) has invited Expressions of Interest (EoI) from eligible organisations for the “joint development and commercialisation” of low dose or paediatric oral formulation of hydroxyurea to treat sickle cell disease in India.
Sickle Cell Anaemia
oIt affects the shape of red blood cells, which carry oxygen to all parts of the body.
oIn sickle cell anaemia, some red blood cells are shaped like sickles or crescent moons.
oThese sickle cells also become rigid and sticky, which can slow or block blood flow.
oIn later stages, individuals may experience severe pain, anaemia, organ damage, and increased susceptibility to infections.
oHydroxyurea reduces pain frequency and prevents long-term complications; transplantation is an option too.
Indian Council of Medical Research (ICMR)
Context: Recently, over the last month and a half, 642 million voters participated in the world's largest democratic exercise, and now vote counting has commenced under the supervision of the returning office.
Related Terms
Returning Officer (RO)
oThis nomination is made in consultation with the State Government or Union Territory Administration.
Context: Recently, the All India Bank Employees' Association (AIBEA) initiated the "Bank Clinic" program aimed at aiding bank customers in resolving grievances.
Bank Clinic
oIt offers guidance to customers on available remedies per RBI guidelines without directly resolving issues.
oBank Clinic fosters goodwill with customers by addressing their concerns.
oIt furnishes banks with valuable feedback, pinpointing areas of service deficiencies for improvement.
All India Bank Employees Association (AIBEA)
Context: Around 373 million citizens across the 27 member states of the European Union are eligible to vote in elections to the European Parliament, which is the only directly elected body of the EU.
European Parliament
oVoting Age: In 21 member states, people aged 18 and above can vote. In Belgium, Germany, Austria, and Malta, the minimum voting age is 16. In Greece, people who turn 17 during the election year can vote, and in Hungary, married individuals can vote regardless of age.
Context: Scientists have recently gained valuable new insights into natural altruism by studying the amoeba Dictyostelium discoideum.
Altruistic amoebae
oA fruiting body is composed of a slender stalk made of dead cells and holds aloft a droplet of spores.
oThey contain information for cells to make two cell surface proteins called TgrB1 and TgrC1.
oThe TgrB1 protein on one cell binds to the TgrC1 protein on another.
Altruism
Context: Pench Tiger Reserve (PTR), Maharashtra, recently reported the first photographic record of a spot-bellied eagle owl.
Spot Bellied Eagle Owl
oThey are found throughout the Indian subcontinent and peninsular Southeast Asia, reaching the southernmost limits of their range in Sri Lanka and 12 degrees north in southern Thailand.
oAs an apex predator, it preys on various animals like rodents, small mammals, reptiles, and insects.
oThe spot-bellied eagle-owl is solitary, territorial, and maintains a distinct home range, characteristic of its behavior as a large owl species.
oIUCN: Least Concern
oWildlife (Protection) Act, 1972: Schedule IV
oCITES: Appendix II.
Pench Tiger Reserve
oThe Madhya Pradesh portion lies in the Satpura ranges.
Context: Recently released data from the Ministry of Agriculture & Farmers Welfare shows that Bihar, Uttar Pradesh, and Rajasthan lead the chart of 1.16 lakh farmers who voluntarily gave up the annual Rs 6,000 PM-Kisan scheme benefits between June 2023 and May 2024.
PM-KISAN Scheme
PM-KISAN Mobile App
Context: India will host the world’s most premier aviation event, the annual general meeting (AGM) of the International Air Transport Association (IATA), next year, after a gap of 42 years.
International Air Transport Association (IATA)
Context: Recently, a Nagpur court handed down a life sentence to Nishant Pradeep kumar Agrawal, a former engineer at BrahMos Aerospace Pvt Ltd, convicting him for espionage on behalf of Pakistan's Inter-Services Intelligence (ISI) and for violating several sections of the Official Secrets Act (OSA) and the IT Act.
Official Secrets Act (OSA) 1923
oThe Act expanded its provisions in 1923 to safeguard government privacy and secrecy, especially concerning national security.
oDefined Obligations: High-ranking government officials, their contractors, and those contracted to protect confidential information are legally bound by the Act.
oIdentification of Foreign Agents: The Act defines "foreign agents" as individuals suspected of working for foreign authorities, posing a threat to national security.
oProhibited Activities: Entering restricted areas or aiding others in doing so, as well as gathering or communicating sensitive information detrimental to national safety, is strictly prohibited.
oPenalties: Violations of the Act, especially those endangering state security, are punishable by imprisonment for up to three years, with the possibility of extension.
BrahMos
Context: Recently, the National Green Tribunal took suo-motu cognizance of a Times of India report titled "How partial combustion fuels your bad-air woes," prompting it to issue notices to the Delhi Pollution Control Committee, Central Pollution Control Board, and the Union Ministry of Environment and Forests and Climate Change.
Partial Combustion of Fuel
oGlobal Temperature Increase: The average global temperature has already risen by 1°C due to the accumulation of greenhouse gases in the atmosphere.
oGlobal Warming: Exceeding a 1.5°C increase in global temperature poses risks such as sea level rise, extreme weather events, biodiversity loss, species extinction, food scarcity, worsened health outcomes, and increased poverty for millions worldwide.
oDue to all these factors, there has been a rise in the air pollution oxidative factor which is said to be the key indicator causing adverse health effects.
National Green Tribunal (NGT)
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