Genome Sequencing Project

Genome Sequencing Project :  Recently, Gujarat became the first state in India to launch a dedicated genome sequencing project for its tribal population.

• About Genome Sequencing Project : The project, titled "Creation of Reference Genome Database for Tribal Population in Gujarat"

o Aims to sequence the genomes of 2,000 individuals from various tribal communities across 17 districts.

o Objectives : Identify genetic predispositions to hereditary diseases such as sickle cell anemia and thalassemia

- Detect genetic markers for conditions like cancer, innate immunity, and other inherited disorders

- Enable early diagnosis and targeted healthcare services based on genetic profiles

- Facilitate personalised health strategies and preventive public health policies

• About Genome Sequencing : Process of determining the entire DNA sequence of an organism’s genome.

o A genome refers to the complete set of DNA, including all of an organism’s genes.

o The process involves identifying the precise order of four DNA bases:

                    → Adenine (A)          → Cytosine (C)

                    → Guanine (G)          → Thymine (T)

o Enabled by automated sequencing technologies and advanced computer software, which help assemble and interpret the large volumes of sequence data.